Senior-Woman-Vaccine

by Brian Shilhavy
Editor, Health Impact News

Medical professionals from Spain have just published a study (April 2018) on the 13-valent pneumococcal conjugate vaccine (PCV13) that is routinely given to older adults to protect against pneumonia. The study was published in the journal BMC Infectious Diseases.

The PCV13 vaccine has been available since 2012, when it was approved by the FDA. The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC) recommends the PCV13 vaccine for persons aged 19–64 years who have high-risk conditions (mainly anatomical or functional asplenia and immunocompromising conditions) and for all persons 65 years or older (with or without risk conditions).

The medical researchers in Spain conducted the study to determine if the vaccine was effective or not in preventing hospitalization from pneumonia.

Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults.

The study was a population-based cohort study that looked at over two million people over the age of 50 residing in Catalonia, Spain. They looked at both vaccinated and unvaccinated adults, noting those who were hospitalized for pneumonia and those who died from any cause.

The results of their study concluded that not only did the PCV13 vaccine not reduce the risk of pneumonia, it actually increased the risk among those vaccinated.

In this study, the large differences in outcomes between PCV13 vaccinated and unvaccinated suggest that vaccinated persons were sicker.

The study also found that the mortality rate was 60% higher in the vaccinated population (5,944 per 100,000) than in the unvaccinated population (2,354 per 100,000).

Evaluating clinical effectiveness of 13-valent pneumococcal conjugate vaccination against pneumonia among middle-aged and older adults in Catalonia: results from the EPIVAC cohort study

BMC Infectious Diseases Published: 27 April 2018

Abstract

Background

Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults.

Methods

Population-based cohort study involving 2,025,730 individuals ≥50 years in Catalonia, Spain, who were prospectively followed from 01/01/2015 to 31/12/2015. Primary outcomes were hospitalisation for pneumococcal or all-cause pneumonia and death from any cause. Cox regression models were used to evaluate the association between PCV13 vaccination and the risk of each outcome, adjusting for age, sex and major comorbidities/underlying risk conditions.

Results

Cohort members were observed for a total of 1,990,701 person-years, of which 6,912 person-years were PCV13 vaccinated. Overall, crude incidence rates (per 100,000 person-years) were 82.8 (95% confidence interval [CI]: 77.7–88.1) for pneumococcal pneumonia, 637.9 (95% CI: 599.0–678.7) for all-cause pneumonia and 2367.2 (95% CI: 2222.8–2518.7) for all-cause death. After multivariable adjustments, we found that the PCV13 vaccination did not alter significantly the risk of pneumococcal pneumonia (multivariable-adjusted hazard ratio [mHR]: 1.17; 95% CI: 0.75–1.83; p = 0.493) and all-cause death (mHR: 1.07; 95% CI: 0.97–1.18; p = 0.190), although it remained significantly associated with an increased risk of all-cause pneumonia (mHR: 1.69; 95% CI: 1.48–1.94; p < 0.001). In stratified analyses focused on middle-aged or elderly persons and immunocompromised or immunocompetent subjects, PCV13 vaccination did not appear effective either.

Conclusion

Our data does not support clinical benefits of PCV13 vaccination against pneumonia among adults in Catalonia. It must be closely monitored in future studies involving more vaccinated person-time at-observation.

Full Study.

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Say NO to Mandatory Vaccines T-Shirt

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100% Pre-shrunk Cotton!

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Make a Statement for Health Freedom!

Big Pharma and government health authorities are trying to pass laws mandating vaccines for all children, and even adults.

Show your opposition to forced vaccinations and support the cause of Vaccine Impact, part of the Health Impact News network.